To develop a prognostic model for neoadjuvant immunochemotherapy efficacy in esophageal squamous cell carcinoma by analyzing the immune microenvironment.

The densities of PD-1+, TIM3+, LAG-3+, CD4+PD-1+, CD4+ LAG-3+, CD8+PD-1+, CD8+TIM3+, CD8+LAG-3+ cells showed a trend of being basically unchanged or decreased after treatment ( Supplementary Figure 3 ), and the change values were not statistically significant (P > 0.05) ( Supplementary Figure 4 ). 3.4 Establishment and verification of the prediction model The 10 variables in Panel 1 and 2 with significant differences between the Non-response and Response groups were analyzed by ROC curve to evaluate their value in predicting the response to neoadjuvant therapy.

also in 53,322 other papers