Network-based elucidation of colon cancer drug resistance mechanisms by phosphoproteomic time-series analysis.

Nat Commun · 2024 · PMC11082183 · PMID 38724493

Europe PMC DOI

hedged sentence

0.1560

closest p · 3.1× alpha

0.1560

boldest claim

The sentences

showed a trendp < 0.156not close (p > 0.1)

Furthermore, indirect interactions removal by stDPI/DPI showed a trend towards higher accuracy (intersection: p < 0.156) but higher network coverage (full: p < 1.9e-6), compared to using a contextualized reference network from LinkPhinder (LP) 16 , and improved on both counts (intersection: p < 0.003, full: p < 4.4e-4) when using HSM 15 as a reference network.

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