Spatial Distribution of Macrophage and Lymphocyte Subtypes within Tumor Microenvironment to Predict Recurrence of Non-Muscle-Invasive Papillary Urothelial Carcinoma after BCG Immunotherapy.

Int J Mol Sci · 2024 · PMC11084693 · PMID 38731992

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0.0522

closest p · 1.0× alpha

0.1000

boldest claim

The sentences

borderline significancep -value = 0.0522so close (0.05 < p ≤ 0.1)

The history of positive repeated TUR (re-TUR) (HR: 4.93, p -value = 0.0001) and T1 tumor stage (HR: 2.04, p -value = 0.0159) were associated with shorter RFS, while G3 tumor grade according to the 1973 WHO classification showed borderline significance (HR: 1.83, p -value = 0.0522).

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did not reach statistical significancep -values > 0.1so close (0.05 < p ≤ 0.1)

Similarly, high-grade tumors, according to the 2004 WHO classification, and ICOS density in the epithelium, did not reach statistical significance ( p -values > 0.1); nevertheless, we tested them in the multivariate analysis (see below). 2.3.

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of borderline significanceno p-value reported

Patients with pT1 stage tumors (HR: 2.04, p -value = 0.0159) and high-grade tumors, according to the 1973 WHO classification (HR: 1.83, p -value = 0.0522), had a higher risk of recurrence, although the latter association was of borderline significance.

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