Association between COVID-19 severity and tobacco smoking status: a retrospective cohort study using propensity score matching weights analysis.

In the analysis of crude estimates, an increase was observed in the odds of severe COVID-19 disease among the ever-smoker group, as measured by the WHO ordinal scale (OR=1.28, 95% CI 0.85 to 1.94, p=0.226), but this did not reach statistical significance.

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Additionally, there were higher odds of non-invasive mechanical ventilation or high-flow nasal cannula usage in the ever-smoker group (7.1% vs 3.1%) with an OR of 1.04 (95% CI 1.00 to 1.08, p=0.058), although this just failed to reach statistical significance.

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