Barely Significant
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Combination administration of alprazolam and N-Ethylmaleimide synergistically enhances sleep behaviors in mice with no potential CNS side effects.

PeerJ · 2024 · PMC11086308 · PMID 38737745

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a significant trendno p-value reported
Notably, a significant trend of benzodiazepine overdose, particularly in older patients susceptible to related adverse events, has been observed in China’s primary healthcare facilities ( Fu et al., 2023 ).

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