Barely Significant
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Hypocretin (Orexin) Replacement Therapies.

Med Drug Discov · 2020 · PMC11086741 · PMID 38738170

Europe PMCDOI
1
hedged sentence
0.0550
closest p · 1.1× alpha
0.0550
boldest claim

The sentences

did not reach statistical significancep = 0.055so close (0.05 < p ≤ 0.1)
Compared to placebo, intranasal Hcrt-1 tended to increase wakefulness in the first half of the night from a median of 33 min to 47.5 min (although the difference did not reach statistical significance (p = 0.055)), and significantly decreased the amount of REM sleep during the second half of the night (median of 35 min to 21 min) and overall (median of 61.8 min to 45.8 min).

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