Subset scanning for multi-trait analysis using GWAS summary statistics.

Bioinformatics · 2024 · PMC11087659 · PMID 38191683

Europe PMC DOI

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marginally significantno p-value reported

After applying TraitScan on the genetic scores, neither of the two genes KIZ ( P -value = 0.0542 ) and RREB1 ( P -value = 1) reached statistical significance in TraitScan, although the trait insulin-like growth factor 1 (IGF-1) picked up by KIZ was marginally significant.

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did not reach statistical significanceno p-value reported

For SNP rs7742053, TraitScan combined test P -value was 0.872 and thus did not reach statistical significance.

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highly significantno p-value reported

It showed traits that were highly significant in PheWAS were also captured by TraitScan.

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