Gas chromatography coupled with mass spectrometry (GC-MS) disclosed that levels of acetate were significantly increased in uninfected Il22ra2 –/– mice compared to their WT counterparts and showed a trend to an increase in cohoused WT mice ( Fig. 5 D ); the latter group of mice also exhibited the highest levels of butyrate ( SI Appendix , Fig.
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Deficiency of IL-22-binding protein enhances the ability of the gut microbiota to protect against enteric pathogens.
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