Even though the expression level of SOD2 protein did not reach statistical significance, significant changes were observed in most key proteins (HIF1A, HMOX1, Keap1, mTOR) involved in anti-hypoxia effects, thereby confirming the anti-hypoxia function of SAL.
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The application of proteomics and phosphoproteomics to reveal the molecular mechanism of salidroside in ameliorating myocardial hypoxia.
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