High-mannose glycans from <i>Schistosoma mansoni</i> eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2.

While no difference was seen in the IL-4 response ( Figure 4H ), cell cultures from egg-immunized mice receiving CIII displayed a nearly significant lower IL-13 ( Figure 4I ) and a decreased IFNγ ( Figure 4J ) response to the antigens, while the IL-17 ( Figure 4K ) and the IL-10 ( Figure 4L ) levels remained unaffected.

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