Previous work on the RHS has reported positive slopes before the age of 5 in those with type 2 SMA followed by a negative slope, whereas the patients with SMA 3a demonstrated an increase in scores before 5 years, stability between ages 5–7 and then a negative trend after 7 years [ 15 ].
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Disease Trajectories in the Revised Hammersmith Scale in a Cohort of Untreated Patients with Spinal Muscular Atrophy types 2 and 3.
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