Liver histology is associated with long-term clinical outcomes in patients with metabolic dysfunction-associated steatohepatitis.

Sensitivity analysis of the association of LI with cirrhosis showed a borderline significant difference in risk of cirrhosis for LI1 versus LI2–3 (HR [95% CI]: 0.44 [0.20–1.00], p = 0.050).

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In both groups (with and without weight-loss surgery), patients with higher fibrosis stages were more likely to have a higher incidence of cardiovascular events versus lower fibrosis stages, although most comparisons did not reach statistical significance.

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