Comparative analysis of bevacizumab and LITT for treating radiation necrosis in previously radiated CNS neoplasms: a systematic review and meta-analysis.

J Neurooncol · 2024 · PMC11093788 · PMID 38619777

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hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

Although this striking difference did not reach statistical significance ( p = 0.09), presumably due to the limited data, the perilesional edema following LITT treatment, which is typically more prevalent and more severe with larger lesions and sometimes poorly tolerated by patients, may explain this observed trend [ 46 ].

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