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A transcriptomic based deconvolution framework for assessing differentiation stages and drug responses of AML.

NPJ Precis Oncol · 2024 · PMC11102519 · PMID 38762545

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Larger groups of AML, however, such as NPM1 mutated cases ( n = 55, R 2 = 0.33, P < 0.001), and AML-NOS ( n = 42, R 2 = 0.17, P = 0.007), together accounting for ~58% of AML, also showed a clear trend for Venetoclax resistance (Fig. 3c ).

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