Combined metagenomic- and culture-based approaches to investigate bacterial strain-level associations with medication-controlled mild-moderate atopic dermatitis.

For example, S hominis LK2134, isolated from a control participant, showed a trend toward improved barrier function ( P adj = .12; P = .005), whereas S hominis LK2024, isolated from a lesional swab, showed the most detrimental effect on barrier function ( P adj < 1 × 10 −10 ).

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