Dual neutrophil subsets exacerbate or suppress inflammation in tuberculosis via IL-1β or PD-L1.

However, transfer of PD-L1 hi regulatory neutrophils relieved inflammation in the lung tissue from IFN-γR −/− mice ( Fig 7G ), although the difference in total lung surface occupied by lesions among mock-treated and regulatory neutrophil transferees did not reach statistical significance ( Fig 7H ).

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