Controversy in cardiology: clopidogrel or acetylsalicylic acid in the treatment of chronic coronary syndromes?

Regarding the secondary endpoints, however, the risk of myocardial infarction was significantly lower with monotherapy with P2Y12 receptor inhibitors compared with monotherapy with ASA (HR 0.77, 95% CI 0.66–0.90; P < 0.001), with an NNT of 136; for stroke, a trend was identified that did not reach statistical significance (HR 0.84, 95% CI 0.70–1.02; P = 0.076), while no difference was found in cardiovascular mortality and mortality from all causes.

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