Deletion of IRE1α in podocytes exacerbates diabetic nephropathy in mice.

Immunofluorescence microscopy showed comparable glomerular expression of the podocyte differentiation markers nephrin and podocalyxin among the 4 groups of mice; there was reduced expression of podocalyxin in mice after 6 months of diabetes, which did not reach statistical significance (Supplementary Fig. 2 ).

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