Single-Cell Analyses Offer Insights into the Different Remodeling Programs of Arteries and Veins.

In contrast, veins showed a higher abundance of endothelial cells, pericytes, and macrophages, as well as an increasing trend in fibroblasts.

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Modulated SMCs, defined by lower expression of contractile markers and upregulation of MYH10 , FN1 , and COL8A1 with respect to contractile SMCs ( Figure S1C, Data Set S1 ), showed a trend toward higher abundance in arteries, whereas fibroblasts had an increasing trend in veins ( DCN , PDGFRA , CFD , C3; Table 1 ).

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