Impact of Replacement Therapy on Pregnancy Outcomes in Hemophilia Carriers: A Historical Cohort Study in Saudi Arabia.

Logistic regression analysis revealed no significant association between adverse events and therapy type or dosage, though a trend towards significance was noted with once-weekly administration ( p = 0.082).

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While the study did not find a significant association between dosage and adverse events, the frequency of administration, particularly once-weekly infusions, showed a trend towards significance ( p = 0.082).

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However, our analysis suggests the necessity of vigilant, continuous monitoring and highly individualized treatment plans, particularly as there was a noticeable trend toward significance in adverse events associated with less frequent dosing during therapy.

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