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Surgical Aortic Valve Replacement and Renal Dysfunction: From Acute Kidney Injury to Chronic Disease.

J Clin Med · 2024 · PMC11122348 · PMID 38792474

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The univariate analysis showed that age (HR 1.06; 95% CI, 1.02 to 1.07; p : 0.04), diabetes (HR 1.05; 95% CI, 1.02 to 1.09; p : 0.03), CKD stages (HR 1.13; 95% CI, 1.04 to 1.22; p : 0.002), aortic cross-clamp time (HR 1.09; 95% CI, 1.05 to 1.16; p : 0.001), and cardiopulmonary bypass time (HR 1.08; 95% CI, 1.08 to 1.22; p : 0.004) were significantly associated with the endpoint, whereas other comorbidities, such as hyperlipidemia and smoking, failed to reach statistical significance.

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