Effects of <i>CYP3A5</i> Genotype on Tacrolimus Pharmacokinetics and Graft-versus-Host Disease Incidence in Allogeneic Hematopoietic Stem Cell Transplantation.

However, intermediate and extensive metabolizers showed a trend toward a higher incidence of moderate to severe AKI (62% vs. 35%, p = 0.11) compared to poor metabolizers, and this trend was also present with respect to the incidence of severe AKI (KDIGO grade 3) (23% vs. 8%, p = 0.15).

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