HGFK1 Enhances the Anti-Tumor Effects of Angiogenesis Inhibitors via Inhibition of CD90+ CSCs in Hepatocellular Carcinoma.

In this study, we found that H1/pORF-Luciferase (H1/pORF-Luc) nanoparticles accumulated in the upper abdomen of BALB/C mice after tail-vein injection; more specifically, they accumulated in the liver, but not in the lungs, heart, spleen, or kidneys ( Figure 4 A), indicating that the systemic administration of H1/pORF-DNA nanoparticles showed a trend of accumulating in the liver.

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