A novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancer.

BMC Cancer · 2005 · PMC1112586 · PMID 15860134

Europe PMC DOI

hedged sentences

0.0070

closest p · 0.1× alpha

0.0500

boldest claim

The sentences

highly significantp = .007actually significant

Interestingly, the 62 patients with benign tumours showed a highly significant decrease in the 12 and 22 genotype frequency (p = .007) with an odds ratio of 0.46 (95% CI 0.26–0.81).

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nominally significantp = 0.05actually significant

In addition, the ovarian cancer patients had a nominally significant decrease in the number of 12 and 22 genotype carriers compared to the controls (p = 0.05) suggesting that the duplication may be protective for the disease with an odds ratio of 0.72 (95% CI, 0.53–0.99).

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