Exploring the "gene-metabolite" network of ischemic stroke with blood stasis and toxin syndrome by integrated transcriptomics and metabolomics strategy.

On the other hand, although the tail-end blood flow perfusion in the disease group exhibited a decreasing trend compared to the control group, there was no statistical significance (Fig. 3 a,b).

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Results with P < 0.05 were considered statistically significant, with P < 0.01 showing a highly significant difference.

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The OPLS-DA score revealed that the NC, disease, and DS groups exhibited a clear trend of separation (Fig. 9 a,b).

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