Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment.

JCI Insight · 2024 · PMC11128202 · PMID 38386420

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Notably, exhaustion markers, such as Lag3 , Pdcd1 , and Ptger4 , showed a trend toward lower expression levels in the Met+Rap–pretreated group.

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