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Impact of disease volume on survival efficacy of triplet therapy for metastatic hormone-sensitive prostate cancer: a systematic review, meta-analysis, and network meta-analysis.

Int J Clin Oncol · 2024 · PMC11129990 · PMID 38582807

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Compared to abiraterone plus ADT, triplet therapy using darolutamide plus docetaxel plus ADT (HR: 0.81, 95%CI 0.62–1.07) and abiraterone plus docetaxel plus ADT (HR: 0.85, 95%CI 0.60–1.20) did not reach statistical significance in terms of improved OS.

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