The protein levels of β-catenin, a key E-cadherin interaction partner that connects AJs to the actin cytoskeleton but also can act as transcriptional regulator 34 , showed a trend for downregulation but this was not statistically significant (Fig. 2 b).
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HIF2α-dependent Dock4/Rac1-signaling regulates formation of adherens junctions and cell polarity in normoxia.
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