highly significantp -value of <0.001
TNF-alpha maintained its strong predictive value with a higher cutoff of >14.3 pg/mL, achieving the highest sensitivity (87%) and specificity (72%) at 72 h, along with the highest AUC of 0.593 and a highly significant p -value of <0.001, as presented in Table 5 , and Figure 1 and Figure 2 .