Variability in plasma rifampicin concentrations and role of SLCO1B1, ABCB1, AADAC2 and CES2 genotypes in Ethiopian patients with tuberculosis.

Infect Dis (Lond) · 2024 · PMC11134291 · PMID 38315168

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closest p · 1.2× alpha

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nearly significantp = 0.06so close (0.05 < p ≤ 0.1)

In univariate analysis, ABCB1 c.4036A>G , AADAC c.841G>A genotypes and rifampicin dose were significant predictors of rifampicin C max ( p ≤ 0.05), and a nearly significant effect was observed for sex ( p = 0.06).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Variability in plasma rifampicin concentrations and role of &lt;i&gt;SLCO1B1&lt;/i&gt;, &lt;i&gt;ABCB1&lt;/i&gt;, &lt;i&gt;AADAC2&lt;/i&gt; and &lt;i&gt;CES2&lt;/i&gt; genotypes in Ethiopian patients with tuberculosis.

The sentences

Variability in plasma rifampicin concentrations and role of <i>SLCO1B1</i>, <i>ABCB1</i>, <i>AADAC2</i> and <i>CES2</i> genotypes in Ethiopian patients with tuberculosis.