HLA dependency and possible clinical relevance of intrathecally synthesized anti-IgLON5 IgG4 in anti-IgLON5 disease.

Front Immunol · 2024 · PMC11141242 · PMID 38827736

Europe PMC DOI

hedged sentences

0.0080

closest p · 0.2× alpha

0.0900

boldest claim

The sentences

highly significantp = 0.008actually significant

However, a similar association with changes in CSF anti-IgLON5 IgG4 was highly significant ( p = 0.008, Figure 4C , right panel), confirming CSF anti-IgLON5 IgG as the major influence on zQ IgLON5-IgG4 .

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failed to reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

However, due to the low number of data points, this difference failed to reach statistical significance ( p = 0.09, Figure 5A , right panel).

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