Anti-inflammatory effects of elexacaftor/tezacaftor/ivacaftor in adults with cystic fibrosis heterozygous for F508del.

PLoS One · 2024 · PMC11142445 · PMID 38820269

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approaching significanceno p-value reported

Consistent with the sera, NLRP3-independent cytokines, TNF (p = 0.0033) and IL-6 (p = 0.0216), were also significantly reduced following ETI therapy, with changes for IL-8 (p = 0.0784) and IL-23 (p = 0.0615) approaching significance.

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