Metabolomic analysis of dietary-restriction-induced attenuation of sarcopenia in prematurely aging DNA repair-deficient mice.

40 The trend for increased GSSG/GSH ratios in Ercc1 ∆/− (and Xpg −/− ) animals compared to WT mice, which did not reach statistical significance (Figure 2B ) might be related to the slightly improved oxidation defence, suggested by the increase of β‐hydroxybutyrate in Xpg −/− mice (Figure 2C ), an important indicator of anti‐aging effects [S1].

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