Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions.

PLoS One · 2024 · PMC11156412 · PMID 38843233

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.0530

boldest claim

The sentences

borderline significantp = 0.052so close (0.05 < p ≤ 0.1)

This was borderline significant in the total population ( p = 0.052) and reached statistical significance when separated by sex, with a preference for male Me1 KO offspring ( p = 0.0187).

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did not reach statistical significancep = 0.053so close (0.05 < p ≤ 0.1)

There was a slight difference between Me1 cKO and FL/FL groups that did not reach statistical significance ( p = 0.053), with control mice averaging 130 ± 10 seconds and cKO mice averaging 90 ± 10 seconds for best performances.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.