Barely Significant
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Genetic variants affecting mitochondrial function provide further insights for kidney disease.

BMC Genomics · 2024 · PMC11163707 · PMID 38858654

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hedged sentence
0.0073
closest p · 0.1× alpha
0.0073
boldest claim

The sentences

showed a trendP = 0.00727actually significant
The mitochondrial haplogroup J, defined by the C295T, T489C, A10398G, A12612G, G13708A and C16069T mutations, showed a trend to higher risk of kidney replacement therapy (OR: 1.957; CI 95% : 1.188–3.178; P = 0.00727), lower eGFR (BETA: -0.115; CI 95% : -0.211-(-0.019); P = 0.0186) and higher SCr levels (BETA: 0.098; CI 95% : 0.015–0.181; P = 0.0201) although not significant after multiple comparisons correction.

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