The progression-free survival (PFS) time was longer in mice that received the combination of Lenti-HPV-07 and anti-TIM3 mAb compared to the mice treated with the Lenti-HPV-07 + Ctrl Ig, even though the difference did not reach statistical significance (Fig. 5e ).
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T-cell immunity induced and reshaped by an anti-HPV immuno-oncotherapeutic lentiviral vector.
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