The open field assay is influenced by room temperature and by drugs that affect core body temperature.

F1000Res · 2023 · PMC11165296 · PMID 38863500

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near-significantno p-value reported

This reduction in CBT was associated with a near-significant increase in distance traveled and center time displayed by WT but not Trpm8 -/- mice, when tested at 4°C ( Figure 6B and C , Figure 5 ).

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