Similarly, we find an overall trend of enrichment of pathways relating to thin skin and dermal atrophy in the RR-5 and RR-7 mice, with suppression occurring in the MHU-2 mice (Fig. 5a ), likely driven by regulatory patterns in the collagen-associated genes.
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Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology.
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Similar to RR-7, RR-5 also showed a trend of upregulation in collagen/ECM genes (Fig. 5a ).