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Effect of Methylfolate, Pyridoxal-5'-Phosphate, and Methylcobalamin (Soloways<sup>TM</sup>) Supplementation on Homocysteine and Low-Density Lipoprotein Cholesterol Levels in Patients with Methylenetetrahydrofolate Reductase, Methionine Synthase, and Methionine Synthase Reductase Polymorphisms: A Randomized Controlled Trial.

Nutrients · 2024 · PMC11173557 · PMID 38892484

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To compare the efficacy within subgroups stratified by genotype, a two-way ANOVA was performed with treatment and genotype as factors, without the need for post hoc tests with Bonferroni correction, as the changes in total cholesterol, HDL-C, triglycerides, and hsCRP did not reach statistical significance.

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