Barely Significant
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Initial eGFR Changes with SGLT2 Inhibitor in Patients With Type 2 Diabetes and Associations With the Risk of Abnormal Serum Potassium Level.

J Am Heart Assoc · 2024 · PMC11179933 · PMID 38686902

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a significant trendno p-value reported
After multivariate adjusting for baseline characteristics, there was a significant trend for an increased risk of all hyperkalemia and hypokalemia events with the increase of initial eGFR decline, specifically for those with an initial eGFR decline of 30% to 40%, 40% to 50%, and >50% following SGLT2i treatment (Figure S6 ).

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