Additionally, we observed positive associations between P‐LCR and total tau ( r = 0.223, p = 0.090; Figure S1 C1 ) and phosphorylated tau ( r = 0.182, p = 0.156; Figure S1 D1 ); however, these associations did not reach statistical significance.
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Correlation analysis of peripheral platelet markers and disease phenotypes in Alzheimer's disease.
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Moreover, P‐LCR emerged as an independent risk factor for AD and exhibited a progressively increasing trend with disease advancement in AD patients, while displaying a decreasing trend in HCs.
The rate of change in P‐LCR showed an increasing trend with disease progression.