Clinical laboratory assessments of coagulation markers showed a trend toward increased D-dimer and prothrombin fragments 1 + 2 values and decreased fibrinogen values with fitusiran vs BPA/CFC prophylaxis ( supplemental Figure 3 ).
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Fitusiran prophylaxis in people with hemophilia A or B who switched from prior BPA/CFC prophylaxis: the ATLAS-PPX trial.
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