However, the MR-Egger and Weighted Median methods provided more cautious assessments that did not reach statistical significance (IA group: MR-Egger: OR: 0.565, P: 0.3863, 95% CI: 0.156–2.046; Weighted Median: OR: 0.6, P: 0.007754, 95% CI: 0.412–0.874; uIA group: MR-Egger: OR: 0.376, P: 0.3601, 95% CI: 0.047–3.032; Weighted Median: OR: 0.437, P: 0.02021, 95% CI: 0.218–0.879; Figure 3 ).
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Early sexual activity lowers the incidence of intracranial aneurysm: a Mendelian randomization investigation.
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