OV induced a sharp reduction of tumor cells accompanied by a distinct molecular phenotype in T-long patients We next quantified cell-type abundance before and after virotherapy using single-cell data and observed a significant trend toward reduced fractions of tumor cells after treatment, particularly in T-long patients ( Figures 2 E and 2F).
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Oncolytic adenovirus in treating malignant ascites: A phase II trial and longitudinal single-cell study.
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