Effects of subclinical hypothyroidism in type II diabetes mellitus patients on biochemical, coagulation, and fibrinolysis status.

Other reported similar relationships between FIB with HbA1c,[ 9 , 10 ] BMI,[ 9 , 10 ] and age.[ 9 ] Several studies examined the effect of FIB in nondiabetic patients; serum FIB was found to be slightly higher in SCH compared to EUT, but it did not reach statistical significance.[ 12 , 13 ] In these studies, the values of FIB were within the normal reference range, except for only one study that reported otherwise, and no significant difference was observed.[ 14 ] A recent meta-analysis examining SCH’s effects on FIB reported that FIB was significantly higher in SCH than in EUT; however, the results showed moderate heterogenicity.

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