Identifying novel proteins for migraine by integrating proteomes from blood and CSF with genome-wide association data.

Conversely, a nonzero estimate obtained from MR analysis may still be observed, even if the associations of SNPs with the outcome are only nominally significant. 39 2.8 Protein–protein interaction, druggability evaluation, and safety evaluation To explore the potential interactions between the identified proteins, we constructed a comprehensive protein–protein interaction network using the STRING database ( https://string‐db.org/ ).

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