approaching significancep = 0.056
In the occipital white matter, ACE‐2 protein level was unaltered across the dementia groups compared to age‐matched controls (Table 2 , Figure 4E ) but was raised in relation to SVD severity ( p = 0.0087) with post‐hoc analysis showing higher levels in severe SVD approaching significance (0 vs. 3; p = 0.056) (Figure 4F ).