The effects of aging, sex, and tumor burden on the peripheral blood immune cell profile and absolute counts.

When compared to healthy people of the same age, the proportion of peripheral immune T cells in tumor patients in the young, middle-aged, and elderly groups showed a significant trend of decline (P <0.0001), and the proportion of T cells in the tumor group gradually decreased with age (young 48.12%, middle-aged 46.09%, and elderly group 43.16%) ( Fig. 3 A ).

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