Copy number variations: The potential association genetic cause in severe cardiovascular diseases with unknown aetiology

J Cell Mol Med · 2024 · PMC11193115

Europe PMC

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did not reach statistical significanceno p-value reported

While CNVs appeared more frequently in hypertensive patients, the association did not reach statistical significance. 91 A study focusing on women identified four CNVs ( PAX8 , PPH2 , HYT3 and BMPR2 ) on chromosome 2 linked to hypertension, underscoring potential gender‐specific differences in CNV maps.

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