Unconventional mechanism of action and resistance to rapalogs in renal cancer.

Proc Natl Acad Sci U S A · 2024 · PMC11194491 · PMID 38861592

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quite significantno p-value reported

Conversely, in XP490, where resistance took the longest (6 to 8 mo), mTORC1 inhibition in nontumor cells accounted for a proportionally smaller, though still quite significant, effect.

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